This simple circuit can be used to program the PIC16F84 and similar "flash memory" type parts. It uses a cheap 555 timer IC to generate the programming voltage from a +5V rail, allowing the circuit to be powered from a computer’s USB port. The 555 timer (IC1) is configured as a free-running oscillator, with a frequency of about 6.5kHz. The output of the timer drives four 100nF capacitors and 1N4148 diodes wir-ed in a Cockroft-Walton voltage multiplier configuration.
The output of the multiplier is switched through to the MCLR/Vpp pin of the PIC during programming via a 4N28 optocoupler. Diodes ZD1 and D5 between the MCLR/Vpp pin and ground clamp the output of the multiplier to about 13.6V, ensuring that the maximum input voltage (Vihh) of the PIC is not exceeded. A 100kΩ resistor pulls the pin down to a valid logic low level (Vil) when the optocoupler is not conducting.
http://www.extremecircuits.net/2010/06/usb-powered-pic-programmer_18.html
